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Updated: Jun 11, 2025
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Sequencing of mRNA from Whole Blood using Nanopore Sequencing
Published on: June 3, 2019
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The Precise Basecalling of Short-Read Nanopore Sequencing
Ziyuan Wang1,2, Mei-Juan Tu3,2, Chengcheng Song4,5,2
1Department of Pharmacy Practice and Science, University of Arizona, Tucson, Arizona, USA.
Biorxiv : the Preprint Server for Biology
|September 30, 2024
Abstract
None:
The nanopore sequencing of short sequences, whose lengths are typically less than 0.3kb therefore comparable with Illumina sequencing techniques, has recently gained wide attention. Here, we design a scheme for training nanopore basecallers that are specialized for short biomolecules. With bioengineered RNA (BioRNA) molecules as examples, we demonstrate the superior accuracy of basecallers trained by our scheme.
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