Examining Penetration and Residual Depth in Modern Acrylic Foldable Intraocular Lenses: A Laboratory Study Using Differential Interference Contrast Microscopy to Compare Hydrophilic and Hydrophobic Materials
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View abstract on PubMed
Summary
This summary is machine-generated.Modern acrylic intraocular lenses (IOLs) are susceptible to scratches, with penetration depth depending on applied force. Careful handling during IOL preparation and implantation is essential to prevent permanent defects.
Area Of Science
- Ophthalmology
- Materials Science
- Biomedical Engineering
Background
- Intraocular lenses (IOLs) require high biocompatibility, flexibility for implantation, and rigidity for stability.
- Optic clarity and optical properties must be maintained throughout the lifespan of the IOL.
- Acrylic materials are commonly used for IOLs, with varying hydrophilic and hydrophobic properties.
Purpose Of The Study
- To mechanically assess acrylic intraocular lenses using scratch tests.
- To determine differences in scratch behavior between hydrophilic and hydrophobic acrylic IOLs based on manufacturing and water content.
- To evaluate the impact of varying forces on IOL surface integrity.
Main Methods
- Scratch tests were conducted on hydrophilic and hydrophobic acrylic IOLs using a Nano Scratch Tester.
- A conical indenter (1 µm tip radius, 90° cone angle) was used.
- Tests were performed at three constant loads (5, 10, 15 mN) with a scratch length of 100 µm and speed of 200 µm/min.
Main Results
- Penetration depth increased with applied load for both hydrophilic (25-37 µm) and hydrophobic (25-57 µm) IOLs.
- Residual depths were lower in hydrophilic (1-4 µm) than hydrophobic (5-17 µm) IOLs.
- Hydrophobic acrylics exhibited a wider plastic deformation zone compared to hydrophilic acrylates.
Conclusions
- Acrylic IOLs are sensitive to scratching, with penetration depth directly related to applied force.
- Residual scratch depth is lower than initial penetration depth and load-dependent.
- Both hydrophilic and hydrophobic acrylic IOLs can be damaged; careful handling is critical during IOL procedures.
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