Related Experiment Video
Updated: Jun 11, 2025
Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Effect of Advanced Platelet-Rich Fibrin and Concentrated Growth Factor on Tissues Around Implants in the Maxillary
Ratika Shrivastava1, Rashmi Ladda2, Mohd Mohsin M Patadiya3
1Department of Periodontology, Rishiraj College of Dental Science and Research Center, Bhopal, Madhya Pradesh, India.
Background And Aim:
Tissue repair surrounding implants is essential for the cosmetic maxillary anterior zone to respond favorably to implant therapy. Grafting platelets from an individual's blood was developed to overcome the esthetic requirements and speed up healing. Advanced platelet-rich fibrin (APRF) and concentrated growth factor (CGF) are used for good healing. Our aim was to evaluate the impact of APRF and CGF on healing of tissues around dental implants in the anterior region of the maxilla.
Materials And Methods:
A total of 60 patients who underwent dental implant placement procedures were included in this study. They were divided into two categories: category 1 consisted of patients who underwent dental implant placement procedures without APRF and CGF (n = 30) and category 2 consisted of patients who underwent dental implant placement procedures with APRF and CGF (n = 30). Assessment of alveolar bone height and bone density was conducted using CBCT at baseline and second, fourth, and sixth month postoperatively.
Results:
The alveolar height and alveolar bone density in APRF group and CGF group patients was greater compared to control group patients at all follow-ups.
Conclusion:
APRF and CGF have a positive effect on the tissues around dental implants, promoting faster and better tissue healing around dental implants.
Related Concept Videos
01:16Clot Retraction and Fibrinolysis
01:22Formation of the Platelet Plug
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...