Related Experiment Video
Updated: May 12, 2026

07:07
Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
11.2K
Restoring Vitality: The Science and Practice of Pulp Revascularization in Endodontics
Krishna P Biswas1, Dhaval Desai2, K Vikram Shetty3
1Department of Endodontics, AIIMS, Guwahati, Assam, India.
Journal of Pharmacy & Bioallied Sciences
|September 30, 2024
Summary
Pulp revascularization revitalizes immature teeth with necrotic pulp. This review details its procedures, benefits, and challenges for endodontic treatment.
Area of Science:
- Endodontics
- Regenerative Dentistry
Background:
- Immature permanent teeth with necrotic pulp and apical periodontitis pose treatment challenges.
- Preserving tooth vitality is crucial for long-term dental health.
Purpose of the Study:
- To comprehensively review the current status of pulp revascularization.
- To analyze its efficacy, challenges, and future directions in endodontics.
Main Methods:
- Critical analysis of existing literature.
- Review of clinical experiences and case studies.
Main Results:
- Pulp revascularization shows promise in vital pulp therapy for immature teeth.
- Current literature highlights various clinical protocols and outcomes.
Conclusions:
- Pulp revascularization is a viable, emerging endodontic treatment.
- Further research is needed to optimize techniques and long-term predictability.
Related Concept Videos
Tissue Renewal without Stem Cells
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
However, failure of such a system...
Overview of Regeneration and Repair
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
Regeneration
All animals have varying degrees of...
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

