Related Experiment Video
Updated: Jun 11, 2025

Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
Evaluating the Long-Term Effects of Orthodontic Treatment on Facial Esthetics and Aging
Vijaysinh R Tanpure1, Firoz B Palagiri2, Nimish A Wajekar1
1Department of Orthodontics and Dentofacial Orthopedics, Rural Dental College, Pravara Institute of Medical Science, Ahmednagar, Maharashtra, India.
Background:
Orthodontic treatment is known to significantly impact facial esthetics, but there is a lack of long-term studies examining its effects, particularly in conjunction with the natural aging process. This study aims to fill this gap by investigating the enduring effects of orthodontic treatment on facial esthetics and aging over a 15-year period.
Materials And Methods:
Three hundred orthodontic patients aged 12 to 25 at the start of treatment were included. Dental alignment, soft tissue transformations, skeletal changes, and patient-reported outcomes were measured objectively. Statistical analyses were conducted to compare pretreatment and post-treatment measurements.
Results:
Significant improvements were observed across various aspects following orthodontic treatment. Dental alignment showed a marked reduction in crowding, with an average decrease of 5.2 mm. Soft tissue transformations revealed notable advancements in lip positioning, averaging 3.8 mm, along with increased lip thickness. Skeletal changes were relatively modest, characterized by subtle alterations in chin positioning and mandibular angles. Patients reported high levels of satisfaction, reflected by an average score of 9.2 on the satisfaction scale. Despite treatment efficacy, the aging process continued to manifest natural changes in skin elasticity and fat distribution over the 15-year follow-up period. These findings underscore the multifaceted nature of orthodontic outcomes and highlight the importance of considering long-term effects on facial esthetics and aging.
Conclusion:
This longitudinal study provides valuable insights into the long-term effects of orthodontic treatment on facial esthetics and aging. It highlights significant improvements in dental alignment and soft tissue transformations, along with sustained patient satisfaction. However, modest skeletal changes and the ongoing aging process emphasize the need for managing patient expectations. These findings can guide practitioners and patients in making informed decisions regarding orthodontic interventions.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
The Effect of Aging on Tissues
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

