Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Plant Breeding and Biotechnology

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.

Issues And Trends In Healthcare Delivery System

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

Bioavailability Enhancement: Drug Permeability Enhancement

Bioavailability Enhancement: Drug Permeability Enhancement

After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...

Pharmacogenomics: Identification of New Drug Targets

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

Microorganisms in Medicine and Therapeutics

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.

iChip

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lymphocytic mastopathy mimicking carcinoma in a non-insulin-dependent diabetic: a case report.

BMC women's health·2026

Same author

Pharmaceutical Inspection Co-operation Scheme: An Overview.

Cureus·2024

Same author

A Comparative Analysis of the Regulatory Framework and Collaborative Environment for Pediatric Medical Device Development in Japan and the United States: Identifying Challenges, Support Mechanisms, and Emerging Opportunities.

Cureus·2024

Same author

The Biosimilar Revolution: Assessing the European Union's Approach to Biosimilarity, Interchangeability, Patient Access, and Its Market Analysis.

Cureus·2024

Same author

A Review of the Regulatory Challenges of Personalized Medicine.

Cureus·2024

Same author

A Comprehensive Analysis of Class I Medical Device Recalls: Unveiling Patterns, Causes and Global Impacts.

Cureus·2024

Search research articles

Related Experiment Video

Updated: May 8, 2026

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

Published on: September 17, 2013

Phytosome Technology: A Novel Breakthrough for the Health Challenges.

Kalaivani P¹, Kamaraj R²

¹Pharmacy, Sri Ramasamy Memorial College of Pharmacy, Chennai, IND.

|September 30, 2024

Summary

Phytosomes, complexes of plant compounds and phospholipids, enhance the bioavailability and effectiveness of phytochemicals. This study explores their preparation, evaluation, and therapeutic potential across various health conditions, showing improved potency over free extracts.

Keywords:

bioavailability herbosomes phospholipids phytosomes target drug delivery

More Related Videos

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Published on: April 14, 2023

Isolation of Soil Microorganisms Using iChip Technology

Isolation of Soil Microorganisms Using iChip Technology

Published on: January 10, 2025

Related Experiment Videos

Last Updated: May 8, 2026

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

Published on: September 17, 2013

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Published on: April 14, 2023

Isolation of Soil Microorganisms Using iChip Technology

Isolation of Soil Microorganisms Using iChip Technology

Published on: January 10, 2025

Area of Science:

Phytochemistry
Nanotechnology
Pharmacology

Background:

Phytochemicals offer therapeutic benefits but suffer from poor solubility and low bioavailability.
Traditional plant extracts often lack efficacy due to poor absorption and metabolism.
Phytosomes represent an advanced delivery system to overcome these limitations.

Purpose of the Study:

To review phytosome preparation methods and evaluation parameters.
To investigate the therapeutic applications of phytosomes in diverse ailments.
To compare the potency of phytosome complexes with free phytochemical extracts.

Main Methods:

Review of literature on phytosome formulation techniques.
Analysis of phytosome characterization and evaluation studies.
Synthesis of data on phytosome efficacy in various disease models.

Main Results:

Phytosomes significantly enhance the absorption and bioavailability of phytochemicals.
Phytosome complexes demonstrate increased potency compared to unformulated plant extracts.
Phytosomes show promise in managing conditions including COVID-19, cancer, diabetes, and inflammatory diseases.

Conclusions:

Phytosomes improve the stability, bioavailability, and therapeutic efficacy of phytochemicals.
Recent phytosome formulations offer effective or alternative treatment options for numerous health conditions.
Phytosome technology is crucial for maximizing the health benefits of plant-derived compounds.