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Updated: Jun 11, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Analysis of Deep Vein Thrombosis: A Prospective Observational Study
Iqbal M Ali1, Vijay Sai Reddy M1, Varun Shetty1
1General Surgery, Dr D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.
This study on deep vein thrombosis (DVT) in India found hypertension, diabetes, obesity, and smoking as key risk factors. Both anticoagulation and thrombolytic therapy showed similar recanalization rates for DVT patients.
Area of Science:
- Vascular Medicine
- Thrombosis Research
- Epidemiology
Background:
- Deep Vein Thrombosis (DVT) is a significant vascular condition with various acquired risk factors.
- Understanding the prevalence and risk factors for DVT is crucial for effective management and prevention strategies.
- Tertiary care centers play a vital role in diagnosing and treating complex cases of DVT.
Purpose of the Study:
- To investigate the prevalence and acquired risk factors of deep vein thrombosis (DVT) in a tertiary care setting in India.
- To evaluate the treatment outcomes of conventional anticoagulation and thrombolytic therapy for DVT.
- To assess the incidence of early recanalization and post-thrombotic syndrome (PTS) following DVT treatment.
Main Methods:
- Prospective observational study conducted from 2022 to 2024, including 100 patients with lower extremity DVT.
- Inclusion of patients from various surgical and medical departments presenting with DVT symptoms.
- Utilized venous Doppler ultrasound for diagnosis and assessed treatment effectiveness of anticoagulation and thrombolysis.
Main Results:
- Highest DVT incidence in the forties (mean age 44.84 years), with a female preponderance (58%).
- Identified key acquired risk factors: smoking (34%), hypertension (25%), history of DVT (25%), diabetes mellitus (20%), and cancer (20%).
- Both anticoagulation and thrombolysis showed similar recanalization rates; thrombolysis led to longer hospital stays and return-to-work periods but less PTS.
Conclusions:
- Recognizing and managing acquired risk factors for DVT is essential for early diagnosis and reduced morbidity/mortality.
- Effective treatment strategies, tailored to individual patient needs, are crucial for better DVT management and prevention.
- Further research can optimize therapeutic approaches to improve long-term outcomes for DVT patients.
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