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[HLA-DR in rheumatoid arthritis]

D B Iakovleva, L I Benevolenskaia, A V Orlov-Morozov

    Terapevticheskii Arkhiv
    |January 1, 1985
    PubMed

    The authors describe the results of HLA-DR typing of 80 patients with rheumatoid arthritis (RA). The patients showed accumulation of HIA-DR (51.25% versus 28.9% in the control), with the relative risk being 2.58. The interrelationship is demonstrated between the clinical picture of RA and HIA-DR antigens: a statistically significant accumulation of HIA-DR4 in the seropositive patterns according to the RF of RA as compared with the seronegative pattern and primary demonstration of HIA-DR3 in RA with the systemic manifestations as compared with the articular pattern.

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