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Bilateral purtscher-like retinopathy associated with DRESS syndrome: a case report
Langxuan Yuan1, Yuchen Li1, Hanze Zhang1
1Department of Ophthalmology, First Affiliated Hospital of Xi'an Jiaotong University, 277# west Yan Ta road, Xi'an, Shaanxi, 710061, China.
Background:
To report a case of Bilateral Purtscher-like retinopathy associated with DRESS syndrome managed with ocular and systemic treatments.
Case Presentation:
A 29-year-old healthy female developed multi-organ (cutaneous, hematologic, renal and hepatic) disfunction and profound vision loss 1 month after Human papillomavirus vaccine injection. At the first presentation, her visual acuity was counting fingers in both eyes. Fundus exam showed remarkable cotton-wool spots, retinal hemorrhages and macular edema. She was diagnosed DRESS syndrome and Purtscher-like retinopathy and treated with intravitreal injection of ranibizumab, systemic steroids anticoagulants, and plasma exchange. The patient finally recovered from this life-threatening condition but left with permanent visual damage.
Conclusion:
Purtscher-like retinopathy could be complicated by DRESS syndrome which is usually considered a type IV hypersensitivity reaction.
