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Updated: Jun 11, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
12-Month Time in Tight Range Improvement with Advanced Hybrid-Closed Loop System in Adults with Type 1 Diabetes
Laura Nigi1,2, Maria De Los Angeles Simon Batzibal3, Dorica Cataldo4
1Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy. laura.nigi@unisi.it.
Introduction:
Time in tight range (TITR) is an emerging and valuable metric for assessing normoglycemia. The latest advancement in automated insulin delivery (AID) systems, the advanced hybrid closed-loop (AHCL) systems, are particularly noteworthy for managing type 1 diabetes (T1D) and enhancing glycemic control.
Methods:
In a real-world clinical setting, we carried out a retrospective evaluation of TITR in 42 adult subjects with T1D using the AHCL Minimed™ 780G system over a 12-month period.
Results:
Within just 14 days of activating the automatic mode, the AHCL Minimed™ 780G system showed rapid improvement in TITR, and in the other continuous glucose monitoring (CGM) metrics. This improvement persisted over 12 months, achieving the proposed 45-50% range for effective glycemic control.
Conclusion:
The AHCL Minimed™ 780G system significantly enhances TITR, demonstrating continuous improvement throughout a 12-month follow-up period.
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