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Evaluating the Efficacy of Immune Checkpoint Inhibitors in Elderly Patients: A Systematic Review and Meta-analysis

Han Sang Kim1,2

  • 1Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. modeerfhs@yuhs.ac.

Methods in Molecular Biology (Clifton, N.J.)
|September 30, 2024
PubMed

Keywords:
AgeElderlyImmune checkpoint inhibitorImmunosenescenceImmunotherapyMeta-analysisSystematic reviewSystemic reviews

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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