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Nerve conduction, latency, and its association with hand function in young men.

Awad M Almuklass^1,2, Abdulmajeed Mansour Alassaf¹, Rakan F Alanazi¹

¹Basic Medical Science Department, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

|September 30, 2024

Summary

Ulnar nerve conduction velocity significantly correlates with hand function, explaining 20% of performance variations in healthy young adults. Other factors also influence this biomarker of neurological health.

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Area of Science:

Neuroscience
Human Physiology
Biomedical Engineering

Background:

The median and ulnar nerves are crucial for hand function, but their precise association requires further investigation.
Existing data are insufficient to quantify the relationship between nerve conduction and hand dexterity.

Purpose of the Study:

To investigate the correlation between hand function, measured by the Grooved Pegboard Test (GPT), and nerve conduction velocity (NCV) and latency of the median and ulnar nerves.
To determine the extent to which ulnar and median nerve conduction parameters predict hand function in healthy young adults.

Main Methods:

Recruited 28 healthy medical students (aged 20-29 years) for the study.
Assessed hand function using the Grooved Pegboard Test (GPT) and hand dominance via the Edinburgh Handedness Inventory (EHI).
Measured nerve conduction velocity (NCV) and latency for both median and ulnar nerves in both hands.

Main Results:

The dominant hand showed significantly faster GPT times compared to the non-dominant hand.
Ulnar nerve NCV in the dominant hand significantly correlated with GPT performance (r = -0.52, p = 0.005).
Ulnar nerve NCV accounted for 20% of the variance in dominant hand GPT performance (R² = 0.203, p = 0.016).

Conclusions:

Ulnar nerve conduction velocity is a significant predictor of hand function, explaining a notable portion of performance variance in healthy young individuals.
While ulnar nerve function is important, other factors also substantially influence hand function and neurological health biomarkers in this population.