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Related Concept Videos

Hypertension I: Introduction01:28

Hypertension I: Introduction

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Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
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The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
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Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
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Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

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Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
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Related Experiment Video

Updated: Jun 11, 2025

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Optimal Blood Pressure Targets with Age.

Mark A Supiano1

  • 1Division of Geriatrics, Spencer Fox Eccles School of Medicine, Center on Aging, University of Utah, 30 North Mario Capecchi Drive, 2nd Floor North, Salt Lake City, UT 84112, USA.

Clinics in Geriatric Medicine
|September 30, 2024
PubMed
Summary

Lowering systolic blood pressure (SBP) in older adults to under 130 mm Hg is recommended for cardiovascular and cognitive health. For some high-risk individuals, an SBP goal of 120 mm Hg may be considered.

Keywords:
Age-friendly careClinical guidelinesCognitive impairmentDementiaPatient-centeredRandomized clinical trialsTherapeutic nihilism

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Area of Science:

  • Gerontology
  • Cardiology
  • Neurology

Background:

  • Older adults (≥65 years) often face elevated cardiovascular disease and cognitive impairment risks.
  • Antihypertensive therapy requires tailored systolic blood pressure (SBP) goals for optimal patient benefit.

Purpose of the Study:

  • To define optimal systolic blood pressure (SBP) target goals for antihypertensive therapy in older adults.
  • To guide the application of benefit-based SBP targets for high-risk elderly populations.

Main Methods:

  • Review of current guidelines and clinical evidence for antihypertensive therapy in older adults.
  • Analysis of benefit-based therapeutic targets for systolic blood pressure (SBP).

Main Results:

  • A systolic blood pressure (SBP) goal of less than 130 mm Hg is favored for most adults aged 65 years and older.
  • A more stringent SBP goal of 120 mm Hg may be appropriate for select high-risk individuals.

Conclusions:

  • Benefit-based systolic blood pressure (SBP) targets are crucial for managing hypertension in older adults.
  • Tailoring SBP goals to individual risk profiles, including cardiovascular and cognitive health, maximizes therapeutic benefits.