Antioxidant potential of exopolysaccharides from lactic acid bacteria: A comprehensive review

Exopolysaccharides (EPSs) from lactic acid bacteria (LAB) have multifunctional capabilities owing to their diverse structural conformations, monosaccharide compositions, functional groups, and molecular weights. A review paper on EPS production and antioxidant potential of different LAB genera has not been thoroughly reviewed. Therefore, the current review provides comprehensive information on the biosynthesis of EPSs, including the isolation source, type, characterization techniques, and application, with a primary focus on their antioxidant potential. According to this review, 17 species of Lactobacillus, five species of Bifidobacterium, four species of Leuconostoc, three species of Weissella, Enterococcus, and Lactococcus, two species of Pediococcus, and one Streptococcus species have been documented to exhibit antioxidant activity. Of the 111 studies comprehensively reviewed, 98 evaluated the radical scavenging activity of EPSs through chemical-based assays, whereas the remaining studies documented the antioxidant activity using cell and animal models. Studies have shown that different LAB genera have a unique capacity to produce homo- (HoPs) and heteropolysaccharides (HePs), with varied carbohydrate compositions, linkages, and molecular weights. Leuconostoc, Weissella, and Pediococcus were the main HoPs producers, whereas the remaining genera were the main HePs producers. Recent trends in EPSs production and blending to improve their properties have also been discussed.