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Updated: Jun 11, 2025

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
First Experience With Catheter-Directed Thrombolysis for Massive Pulmonary Embolism at Teaching Hospital Jaffna, Sri
Kajananan Sivagurunathan1, Pirannavan Ratnasingam2, Dilan Jayanthan2
1Internal Medicine, Teaching Hospital Jaffna, Jaffna, LKA.
Catheter-directed thrombolysis (CDT) is one of the modes of treatment for massive pulmonary embolism (PE). This case report shares the new experience of CDT for massive PE at Teaching Hospital Jaffna, Sri Lanka. A 54-year-old woman developed massive PE two days after a traumatic tibial fracture. She was hemodynamically unstable with hypotension and hypoxemia. The multidisciplinary team decided to go for CDT, administering alteplase. Follow-up imaging demonstrated complete thrombus resolution and significant clinical improvement. This case emphasizes the efficacy and safety of CDT for massive PE, particularly in patients at high risk for bleeding. Our experience at Teaching Hospital Jaffna accentuates the significance of individualized treatment strategies and the adoption of advanced techniques in resource-limited settings.
Catheter-directed thrombolysis (CDT) is one of the modes of treatment for massive pulmonary embolism (PE). This case report shares the new experience of CDT for massive PE at Teaching Hospital Jaffna, Sri Lanka. A 54-year-old woman developed massive PE two days after a traumatic tibial fracture. She was hemodynamically unstable with hypotension and hypoxemia. The multidisciplinary team decided to go for CDT, administering alteplase. Follow-up imaging demonstrated complete thrombus resolution and significant clinical improvement. This case emphasizes the efficacy and safety of CDT for massive PE, particularly in patients at high risk for bleeding. Our experience at Teaching Hospital Jaffna accentuates the significance of individualized treatment strategies and the adoption of advanced techniques in resource-limited settings.
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