Frontal Glioblastoma Presenting With Catatonia: A Case Report

This case highlights the need for thorough medical and neurological screening before making any psychiatric diagnosis, even if the patient has a classical syndromic presentation. Presented here is a case of a female in her late 40s coming to our psychiatric outpatient with symptoms suggestive of catatonia. She was treated at a private clinic for depression. As her symptoms deteriorated, she was brought to our hospital for further management. She was diagnosed with catatonia during admission assessment. A detailed neurological assessment later revealed slight weakness in the right upper and lower limb. Following this, a CT scan was done and was reported to have a hypodense area involving the bilateral frontal and basifrontal region, more pronounced on the left side (likely to be acute/subacute). MRI was subsequently done and was found to be suggestive of glioblastoma NOS (not otherwise specified) involving the bilateral cerebral hemisphere which was later confirmed by the histopathology report.