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Erythrasma: Pathogenesis and Diagnostic Challenges.
Jesús Iván Martínez-Ortega1,2, Samantha Franco González3
1Dermatology, Dermatology Institute of Jalisco, Zapopan, MEX.
Cureus
|October 1, 2024
Summary
Erythrasma, a skin infection by Corynebacterium minutissimum, presents with coral-red fluorescence. Topical clindamycin effectively treated a patient, highlighting the need for accurate diagnosis and management of this common condition.
Area of Science:
- Dermatology
- Microbiology
Background:
- Erythrasma is a superficial bacterial skin infection.
- It is caused by Corynebacterium minutissimum, a normal skin flora inhabitant.
- Pathogenesis remains understudied despite clinical relevance.
Observation:
- A 43-year-old woman with comorbidities presented with an erythematous eczematous plaque.
- Lesions showed characteristic coral-red fluorescence under Wood's lamp.
- Fungal infections were ruled out by negative skin scrapings.
Findings:
- Diagnosis of erythrasma was confirmed.
- A two-week course of topical clindamycin led to complete resolution.
- Corynebacterium minutissimum releases porphyrins causing fluorescence.
Implications:
- Accurate diagnosis and effective treatment are crucial, especially with comorbidities.
- Topical treatments offer convenience for erythrasma.
- Further research is needed to validate the role of hydrophobic/lipophilic interactions in pathogenesis.
Keywords:
coproporphyrin iiicorynebacterium minutissimumdiagnostic techniquesdifferential diagnosiserythrasmapathogenesisporphyrinsultraviolet-induced fluorescence dermoscopyuv led lightwood's lampMore Related Videos
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