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Diversity of Antigen Receptors

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...

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A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy

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Allogeneic and other innovative chimeric antigen receptor platforms

Andrew P Jallouk¹, Salyka Sengsayadeth¹, Bipin N Savani¹

¹Medicine, Hematology Oncology Vanderbilt University Medical Center.

Clinical Hematology International

|October 1, 2024

Summary

No abstract available in PubMed .

Keywords:

Allogeneic Chimeric antigen receptor Engineered cellular therapy Macrophage Natural killer cell T cell

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