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Pulmonary artery mass with PIK3CA mutation after orthotopic heart transplantation
Andre Y Son1, Aaron J Clark2, Borislav A Alexiev3
1Division of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Northwestern Medicine, 676 N St Clair Street Suite 730, Chicago, IL, 60611-2968, USA. ayson90@gmail.com.
Background:
Patients can develop de novo malignancies following orthotopic heart transplantation. However, vascular tumors are not commonly described in this population.
Case Presentation:
We present a 69-year-old female with a history of orthotopic heart transplantation for chemotherapy-induced cardiomyopathy who developed an incidental pulmonary artery mass six years after her transplantation. Given concerns for malignancy, the patient underwent an operative excisional biopsy through a left anterior mini-thoracotomy with femoral artery and vein cannulation for cardiopulmonary bypass. The mass was determined to be a non-malignant vascular overgrowth with PIK3CA mutation.
Conclusion:
We present the case of an unusual pulmonary artery mass with PIK3CA mutation found in a post heart transplant patient. We were able to spare her the morbidity of a redo-sternotomy by excising the mass via a minimally invasive left anterior thoracotomy approach.
