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An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
Published on: May 24, 2024
Integrated 68 Ga-Pentixafor and 68 Ga-FAPI-04 PET/MR for Diagnosing Adrenal Aldosterone-Producing Adenoma and
Jie Ding1, Weilun Wang, Xing Chen
1From the Department of Nuclear Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Abstract:
A 57-year-old man with primary aldosteronism exhibited multiple nodules in the left adrenal, pancreatic tail, and splenic region. The left adrenal nodule showed positive 68 Ga-pentixafor and negative 68 Ga-FAPI-04 uptake, suggesting an aldosterone-producing adrenal adenoma. The nodule in the pancreatic tail exhibited high 68 Ga-pentixafor and low 68 Ga-FAPI-04 uptake, similarity with the nodule in splenic region, indicating accessory splenic nodule. Postoperative pathology confirmed an adrenal cortical adenoma and an accessory splenic nodule in the pancreas. This case underscores the complementary role of 68 Ga-pentixafor and 68 Ga-FAPI-04 PET/MR in diagnosing complex adrenal and pancreatic pathologies.
