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Updated: Jun 11, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

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Point-of-Care Testing for Cardiovascular Disease: A Narrative Review

Xiaolong Liu1,2,3, Mengxiao He4, Rongbo Hu5

  • 1School of Life and Environmental Science, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, China.

Current Medicinal Chemistry
|October 2, 2024
PubMed

Insights

Point-of-care testing (POCT) innovations are vital for managing cardiovascular disease. This review analyzes current POCT methods, highlighting their applications, effectiveness, and future potential for early diagnosis and treatment.

Area of Science:

  • Biomedical Engineering
  • Clinical Diagnostics
  • Public Health

Background:

  • Cardiovascular disease (CVD) presents a significant global health burden.
  • Point-of-care testing (POCT) is essential for CVD prevention, early diagnosis, and management.
  • A variety of POCT technologies exist, each with unique applications and performance characteristics.

Purpose of the Study:

  • To provide a comprehensive analysis of current POCT technologies for cardiovascular disease.
  • To assess the effectiveness and limitations of various POCT methods.
  • To offer insights into future research and clinical applications of POCT in CVD.

Main Methods:

  • Review of existing literature on POCT for cardiovascular disease.
  • Analysis of conventional methods, paper-based microfluidics, microfluidic chips, electrochemical, ultrasonic, and smartphone-based detection technologies.
  • Evaluation of performance across different detection scenarios.

Main Results:

  • Diverse POCT technologies demonstrate varied applications and performance in cardiovascular disease detection.
  • Conventional and advanced methods like microfluidics and electrochemical sensors show promise.
  • Smartphone-based technologies offer potential for accessible, widespread use.

Conclusions:

  • POCT technologies are critical for improving cardiovascular disease outcomes.
  • Understanding the strengths and weaknesses of each POCT method is key for clinical implementation.
  • Continued innovation in POCT will drive advancements in cardiovascular care.

Keywords:
Cardiovascular diseaseelectrochemical detectionmicrofluidic chippaper-based microfluidicpoint-of-care testingsmartphone-based detection.ultrasonic detection

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