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Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System
Published on: May 12, 2023
The Usefulness of Cardiopulmonary Exercise Testing to Detect Functional Improvement after Transcatheter Valve
Luca Cumitini1,2, Ailia Giubertoni2, Giuseppe Patti1,2
1Department of Translational Medicine, University of Eastern Piedmont, 28100 Novara, Italy.
Insights
Cardiopulmonary exercise testing (CPET) helps assess functional capacity in patients undergoing transcatheter valve procedures. This review explores CPET
Area of Science:
- Cardiology
- Cardiopulmonary Physiology
- Interventional Cardiology
Background:
- Transcatheter valve procedures are crucial for high-risk patients with valvular heart disease.
- Cardiopulmonary exercise testing (CPET) is the gold standard for assessing functional capacity, especially in heart failure (HF).
- CPET aids in understanding HF pathophysiology and prognosis.
Purpose of the Study:
- To review the evidence on using CPET to evaluate functional improvement after transcatheter valve procedures.
- To determine the prognostic value of CPET-assessed functional capacity changes in this patient group.
Main Methods:
- Systematic review of existing literature.
- Analysis of studies reporting CPET data before and after transcatheter valve interventions.
- Focus on patients with aortic stenosis, mitral regurgitation, and tricuspid regurgitation.
Main Results:
- Limited data currently exist on the role of CPET in assessing functional capacity changes post-transcatheter valve procedures.
- Functional improvement post-procedure may have clinical relevance and prognostic implications.
- Further research is needed to fully establish the utility of CPET in this context.
Conclusions:
- CPET holds potential for assessing functional gains after transcatheter valve interventions.
- More studies are required to validate its prognostic value and clinical utility.
- Integrating CPET may enhance patient management and risk stratification.
Abstract:
Transcatheter valve procedures have become a cornerstone in the management of patients with valvular heart disease and high surgical risk, especially for aortic stenosis and mitral and tricuspid regurgitation. Cardiopulmonary exercise testing (CPET) is generally considered the gold standard for objectively quantifying functional capacity, providing a comprehensive evaluation of the human body's performance, particularly in patients with heart failure (HF). Its accurate assessment is valuable for exploring the pathogenetic mechanisms implicated in HF-related functional impairment. It is also useful for objectively staging the clinical severity and the prognosis of the disease. The improvement in functional capacity after transcatheter valve procedures may be clinically relevant and may provide prognostic information, even in this setting. However, it remains to be fully determined as data on the topic are limited. This review aims to summarize the available evidence on the usefulness of CPET to assess functional improvement in patients undergoing transcatheter valve procedures.
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