Related Experiment Video
Updated: Jun 11, 2025

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
Published on: September 20, 2018
Revisiting Fournier Gangrene: A Contemporary Epidemiological Perspective vs Perineal Cellulitis
Behzad Abbasi1, Emily Hacker1, Umar Ghaffar1
1Department of Urology, University of California San Francisco, San Francisco, California.
Fournier gangrene (FG) is linked to specific risk factors like Native American race, diabetes, and malignancy, differing from perineal cellulitis. Understanding these factors and improving FG care can reduce mortality.
Area of Science:
- Urology
- Infectious Disease Epidemiology
Background:
- Fournier gangrene (FG) is a severe necrotizing infection of the perineum and genitalia.
- Comparing FG to less severe conditions like perineal cellulitis aids in understanding its unique risk factors and outcomes.
Purpose of the Study:
- To compare the risk factors and mortality associated with Fournier gangrene (FG) versus perineal cellulitis.
- To identify demographic, comorbidity, and clinical factors influencing FG diagnosis and outcomes.
Main Methods:
- A population-based analysis using National Inpatient Sample data from 2016-2020.
- Identification of FG and perineal cellulitis cases, with extraction of demographic, comorbidity, and procedural data.
- Logistic regression models were employed to assess risk factors for FG diagnosis and mortality.
Main Results:
- Over 73,000 cellulitis and 9,300 FG cases were analyzed.
- FG diagnosis was associated with Native American race, weekend/December admissions, diabetes mellitus, and malignancy.
- Hispanic and Asian/Pacific Islander races, and higher income, were linked to reduced FG likelihood. Female sex, Native American ethnicity, and procedural frequency increased FG mortality risk.
Conclusions:
- Patient and clinical factors significantly influence FG development and mortality compared to perineal cellulitis.
- Enhanced understanding of FG and improved access to care are crucial for better patient outcomes.
Related Concept Videos
Urinary Tract Infection II: Pathophysiology
Peripheral Artery Disease V: Postoperative Nursing Management
Acute Pyelonephritis I: Introduction
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Nursing Assessment of the Genitourinary System I: Health History

