Related Experiment Video
Updated: Jun 11, 2025

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Understanding excess mortality in 2022: The dual impact of COVID-19 and heatwaves on the Italian elderly population
Emiliano Ceccarelli1, Giada Minelli2, Antonello Maruotti3
1Department of Statistical Sciences, La Sapienza University, Piazzale Aldo Moro, 5, Rome, 00185, Italy; Statistical Service, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome, 00161, Italy.
Abstract:
In this study, we employ a comprehensive approach to model the concurrent effects of the COVID-19 epidemic and heatwaves on all-cause excess mortality. Our investigation uncovers distinct peaks in excess mortality, notably among individuals aged 80 years and older, revealing a strong positive correlation with excess temperatures (ET) during the summer of 2022 in Italy. Furthermore, we identify a notable role played by COVID-19 hospitalizations, exhibiting regional disparities, particularly during the winter months. Leveraging functional data regression, we offer robust and coherent insights into the excess mortality trends observed in Italy throughout 2022.
Related Concept Videos
Increased Body Temperature
Homeostatic Imbalances in Body Temperature
Factors Affecting Body Temperature
Factors may include:
The Effect of Aging on Tissues
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

