Related Experiment Video

Updated: Jun 11, 2025

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

1.8K

Thrombus Burden, Caval Thrombosis, and Retrieval of the Denali Inferior Vena Cava Filter

Vansh S Jain1, Christine Johnstad1, Sofia Ferrer1

  • 1University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Journal of Vascular and Interventional Radiology : JVIR
|October 2, 2024
PubMed

Insights

The Denali inferior vena cava filter demonstrated a high retrieval success rate of 99.3% with no reported device fractures or migrations. Post-retrieval imaging revealed minimal thrombus in a small percentage of patients.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Medical Device Evaluation

Background:

  • Inferior vena cava (IVC) filters are crucial for preventing pulmonary embolism in high-risk patients.
  • Evaluating the long-term outcomes and retrieval success of specific IVC filter models is essential for clinical practice.
  • The Denali IVC filter is a commonly used device, necessitating a thorough assessment of its performance.

Purpose of the Study:

  • To assess the clinical outcomes and retrieval efficacy of the Denali inferior vena cava filter.
  • To identify any complications associated with the Denali filter, including thrombus formation and device integrity.
  • To evaluate the safety and success rates of filter retrieval procedures.

Main Methods:

  • Retrospective analysis of 508 Denali IVC filter placements in 500 patients between 2015 and 2022.
  • Detailed review of filter retrieval procedures, success rates, and complications.
  • Assessment of imaging data, including venograms and contrast-enhanced imaging, to evaluate for thrombus and caval abnormalities.

Main Results:

  • An overall retrieval success rate of 99.3% was achieved, with 275 initial successful retrievals and 7 successful second attempts.
  • No instances of filter fracture, migration, or clinically significant extravascular strut penetration were reported.
  • Initial retrieval venograms showed clot in filter in 6.3% and caval occlusion in 4.2% of cases. Post-retrieval imaging in a subset revealed thrombus within the filter (8.9%) or caval thrombosis/occlusion/stenosis (8.9%).

Conclusions:

  • The Denali inferior vena cava filter exhibits a high retrieval success rate and a favorable safety profile.
  • Complications such as filter fracture, migration, and significant thrombus formation appear to be infrequent with this device.
  • The Denali filter is a safe and effective option for IVC filtration with successful retrieval outcomes.

More Related Videos

Author Spotlight: Utilizing Venoplasty Balloon Model in Rodents to Simulate Surgical Interventions for Deep Veins05:44

Author Spotlight: Utilizing Venoplasty Balloon Model in Rodents to Simulate Surgical Interventions for Deep Veins

Published on: May 24, 2024

581
Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography06:44

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography

Published on: April 13, 2018

9.9K

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
3
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
3
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
3
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
3
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
3
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
6