Related Experiment Video
Updated: Jun 11, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Assessing the Impact of Consultant Pharmacist-Directed Anticoagulation Management in the Post-Acute and Long-Term
Alexandra Schifano1, Alexandra Statczar1, Anne Metzger1
11 University of Cincinnati, James L. Winkle College of Pharmacy, Cincinnati, Ohio.
Insights
Consultant pharmacist interventions significantly improved anticoagulant therapy management in post-acute and long-term care (PALTC) settings. A high percentage of medication-related problems were identified and addressed, highlighting the value of pharmacist-led anticoagulation services.
Area of Science:
- Pharmacology
- Geriatrics
- Healthcare Management
Background:
- Anticoagulant therapy is crucial for preventing thromboembolic events in elderly patients.
- Managing anticoagulation in post-acute and long-term care (PALTC) facilities presents unique challenges.
- Pharmacist involvement can optimize medication safety and efficacy.
Purpose of the Study:
- To evaluate the impact of consultant pharmacist-directed anticoagulation management.
- To assess the frequency of medication-related problems in anticoagulation therapy within PALTC.
- To determine the rate of provider acceptance of pharmacist recommendations.
Main Methods:
- Retrospective study analyzing data from the ASCP (American Society of Consultant Pharmacists) Quality Improvement Project.
- Inclusion of patients over 65 years old receiving anticoagulation in PALTC facilities.
- Monthly chart reviews by pharmacists and tracking of interventions and provider responses.
Main Results:
- 807 charts were assessed; 274 patients were on anticoagulation.
- 63% of patients on anticoagulation had medication-related problems.
- Pharmacists made 216 recommendations, with 88% accepted by providers.
Conclusions:
- Consultant pharmacist involvement is vital for effective anticoagulation management in PALTC.
- Significant opportunities exist to improve patient safety through pharmacist interventions.
- Further research is needed to explore patient-specific outcomes related to pharmacist management.
Abstract:
Objective: The objective is to evaluate the impact of consultant pharmacist-directed anticoagulation management in the post-acute and long-term care (PALTC) setting. Design: Retrospective study. Participants: Patients whose clinical details were included in the ASCP aggregate data and were older than 65 years of age, admitted to PALTC facility, and had active anticoagulant therapy were included in the study. Interventions: Pharmacists enrolled in the ASCP (Quality Improvement Project) and performed monthly chart reviews per standard practice. The 30-day post-chart review follow-up data were entered into the ASCP data collection. The research team assessed for consultant pharmacist interventions associated with anticoagulant therapy management. Results: Data were collected from November 2022 through March 2023, during which 807 charts were assessed. Within the charts reviewed, 274 patients received anticoagulation therapy, of which 173 (63%) were identified as having a medication-related problem concerning anticoagulant use. Two hundred sixteen pharmacist recommendations were sent to providers to address the inappropriate anticoagulant therapy. Providers completed modifications to 190 (88%) of the recommendations. Conclusion: This study emphasized pharmacist involvement in managing anticoagulant therapy within the PALTC setting and identified the need for further investigation of patient specific outcomes.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Peripheral Artery Disease III: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis IV: Nursing Management
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...

