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Formation of the Platelet Plug01:22

Formation of the Platelet Plug

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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
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Updated: Jun 11, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
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A Vascular Plug for Persistent Shock Following Transcatheter Mitral Valve Replacement.

Asad J Torabi1, Purva Patel2, Natalia Reborido1

  • 1Division of Cardiovascular Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

JACC. Case Reports
|October 3, 2024
PubMed
Summary
This summary is machine-generated.

Transcatheter mitral valve replacement successfully treated severe valve degeneration. However, left ventricular perforation caused cardiogenic shock, highlighting the need for careful post-procedure monitoring in transcatheter valvular interventions.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Severe bioprosthetic mitral valve degeneration poses significant risks.
Keywords:
cardiac tamponadeleft ventricular perforationtranscatheter mitral valve replacement

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  • Transcatheter valve-in-valve procedures offer a minimally invasive treatment option.
  • Complications following transcatheter procedures require prompt recognition and management.