Related Experiment Video
Updated: Jun 11, 2025

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Published on: May 26, 2015
Ultrasonographic Study of the Corkscrew Arterial Image in Buerger Disease Patients
Kaori Homma1, Tomoko Kagayama1, Takehisa Iwai2
1Vascular Lab, Tsukuba Vascular Center, Moriya, Ibaraki, Japan.
Insights
Ultrasonography can identify corkscrew arterial findings in Buerger disease, revealing their association with nerves. These corkscrew vessels may serve as crucial collateral circulation, aiding in diagnosis and management of this intractable vascular condition.
Area of Science:
- Vascular Surgery
- Diagnostic Imaging
- Medical Ultrasonography
Background:
- Thromboangiitis obliterans (Buerger disease) is a severe vascular condition leading to limb amputation.
- Corkscrew (CS) arterial formations are key diagnostic markers, traditionally identified via angiography.
- Modern ultrasonography now enables visualization of these CS findings.
Purpose of the Study:
- To investigate the utility of ultrasonography in identifying corkscrew (CS) arterial findings in Buerger disease.
- To analyze the anatomical relationship between CS formations and surrounding nerves and arteries.
Main Methods:
- Utilized ultrasonographic techniques in 22 Buerger disease cases across 48 study areas.
- Focused on identifying and characterizing CS formations and their proximity to neural structures and main arteries.
Main Results:
- Successfully identified CS formations using ultrasonography in all cases.
- Confirmed CS formations run within or alongside nerve sheaths, suggesting a collateral blood supply role.
- Observed well-developed, normal vessel-like anatomy in these CS collateral vessels.
Conclusions:
- Ultrasonography is effective for detecting corkscrew arterial findings in Buerger disease.
- CS formations are frequently associated with nerves, acting as collateral circulation.
- Diagnostic imaging should extend beyond main arteries to nerve pathways for comprehensive Buerger disease assessment.
Abstract:
Objective: Thromboangiitis obliterans (Buerger disease) is known as an intractable vascular disease that has been reported as thrombosis in distal arteries and occasional venous occlusion, as well as inflammatory changes in the thrombus and vascular wall. Patients often require limb amputation due to limb necrosis. Corkscrew (CS), a small arterial coiling, is an important diagnostic finding that was mainly found with angiography. Recently, however, it can also be identified using a modern ultrasonographic technique. Methods: In these 22 cases, in 48 areas of study, we used the ultrasonographic technique to identify the CS, which allowed us to observe its relationship with the surrounding nerves and arteries. Results: In all cases, it was possible to identify the CS easily and it was confirmed that the CS and the nerve were carried down in their sheath. The sites of the CS existed in areas other than the area around the occluded main arteries and some CS that ran inside the nerve (16 areas) and some CS that accompanied the outside of the nerve (10 areas) were confirmed, suggesting the CS work as collateral blood supply vessels, with well-developed normal vessel-like anatomy. Conclusion: When we observe the CS, it is important to observe not only around the main trunk artery but also areas where nerves mainly run, even if they do not accompany the main trunk artery. (This is a translation of Jpn J Vasc Surg 2023; 32: 345-350.).
More Related Videos
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...

