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Multivalvular Endocarditis With Granulicatella adiacens in a 2-Year-Old Boy With Ventricular Septal Defect

Christopher Schmitt1,2, Ranjit Philip1,2, Christopher Knott-Craig1,2

  • 1Le Bonheur Children's Hospital, Heart Institute, Memphis, Tennessee, USA.

JACC. Case Reports
|October 3, 2024
PubMed

Insights

A pediatric case of polyvalvular endocarditis caused by Granulicatella adiacens required valve replacement. This highlights the importance of updated diagnostic criteria for cardiovascular infections.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Pediatric Medicine

Background:

  • Infective endocarditis is a serious infection affecting heart valves.
  • Accurate etiological diagnosis is crucial for effective treatment.
  • The Duke criteria are standard for diagnosing infective endocarditis.

Observation:

  • A 2-year-old boy presented with polyvalvular endocarditis.
  • The patient had a hemodynamically insignificant ventricular septal defect.
  • Cardiac valve replacement surgery was necessary.

Findings:

  • Blood cultures identified Granulicatella adiacens as the causative pathogen.
  • This pathogen met the microbiological criterion of the updated Duke International Society for Cardiovascular Infectious Diseases criteria.
  • The patient underwent successful pulmonary and mitral valve replacement.

Implications:

  • This case underscores the utility of the updated Duke criteria in diagnosing rare causes of infective endocarditis.
  • Early recognition and appropriate management of Granulicatella adiacens endocarditis are vital in pediatric patients.
  • Surgical intervention is critical for managing severe valvular damage in pediatric infective endocarditis.

Keywords:
Duke criteriainfective endocarditisventricular septal defects

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