Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hematopoiesis

Hematopoiesis

The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...

Overview of Hematopoiesis

Overview of Hematopoiesis

Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Filamin protects myofibrils from contractile damage through changes in its mechanosensory region.

PLoS genetics·2024

Same author

Outcomes of Rural Men with Breast Cancer: A Multicenter Population Based Retrospective Cohort Study.

Cancers·2023

Same author

The unexpected versatility of ALP/Enigma family proteins.

Frontiers in cell and developmental biology·2022

Same author

Slik phosphorylation of Talin T152 is crucial for proper Talin recruitment and maintenance of muscle attachment in <i>Drosophila</i>.

Development (Cambridge, England)·2019

Same author

Extrapelvic Metastases in Endometrial Stromal Sarcomas: A Clinicopathological Review With Immunohistochemical and Molecular Characterization.

International journal of surgical pathology·2018

Search research articles

Related Experiment Video

Updated: May 3, 2026

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

Case Report: Extramedullary Hematopoiesis in the Prostate.

Lucas A B Fisher¹, Nicholas Baniak¹

¹Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

International Journal of Surgical Pathology

|October 3, 2024

Summary

Extramedullary hematopoiesis, a rare condition outside the bone marrow, was found in a prostate core biopsy. This case highlights a second documented instance of this unusual finding in the prostate.

Keywords:

extramedullary hematopoiesis prostate

More Related Videos

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

Published on: November 4, 2022

Related Experiment Videos

Last Updated: May 3, 2026

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

Published on: November 4, 2022

Area of Science:

Urology
Hematology
Pathology

Background:

Extramedullary hematopoiesis (EMH) is the formation of blood cells outside the bone marrow.
EMH typically occurs in the spleen, liver, and lymph nodes.
Prostate EMH is exceptionally rare, with only one prior report in English literature.

Purpose of the Study:

To report a second case of extramedullary hematopoiesis in the prostate.
To describe the clinical and pathological findings of prostate EMH.

Main Methods:

Case presentation of a 56-year-old male patient.
Digital rectal examination and ultrasound findings.
Prostate core biopsy for histopathological confirmation.

Main Results:

A palpable nodule was detected during digital rectal examination.
Ultrasound revealed distinct findings suggestive of the nodule.
Histopathology confirmed extramedullary hematopoiesis within the prostate core.

Conclusions:

Extramedullary hematopoiesis can occur in the prostate, though extremely rare.
This case adds to the limited documented evidence of prostate EMH.
Recognition of prostate EMH is important for accurate diagnosis and to avoid misinterpretation.