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Time and Temperature Dependence of Drug Crystallization─The Role of Molecular Mobility

N S Krishna Kumar1, Rahul Lalge1, Raj Suryanarayanan1

  • 1Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, United States.

Molecular Pharmaceutics
|October 3, 2024
PubMed

Keywords:
Soluplusactivation energyamorphous solid dispersioncrystallizationdrug-polymer interactionshydroxypropyl methylcellulose acetate succinate (HPMCAS)molecular mobilitynifedipinenucleationpolyvinylpyrrolidone vinyl acetate (PVPVA64)time−temperature−transformation

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