Effects of neurosurgical treatment on diffuse slow spike and wave complex: a case of left frontal mass lesion with...

A 10-year-old girl with a mass lesion in the left deep frontal lobe was reported. Clinically, seizures occurred at 3 years and 8 months and became intractable around the age of 5.5 years. EEG initially showed focal spikes on the left fronto-central area and later developed into diffuse slow spike and wave complexes (DSSW). Her seizures were clinically different from those in Lennox-Gastaut syndrome. After a left frontal lobectomy, her intractable seizures completely disappeared with marked EEG improvement and without any neurological deficit. Radiological findings before the operation suggested that the expanding effects extended to the deep temporal structures, adjacent to the frontal lobe. These structures, deep frontal and temporal lobes, both or either, were assumed to be involved in generating DSSW in this case.