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Updated: Jun 11, 2025

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
Published on: September 30, 2021
Unravelling Acquired Hemophilia A in an Ambiguous Clinical Picture
Fathima Shehnaz Ayoobkhan1, Dakshin S Padmanabhan1, Rula Mahayni2
1Internal Medicine, Trinity Health Oakland Hospital, Pontiac, USA.
Abstract:
Acquired hemophilia A (AHA) is characterized by the development of neutralizing autoantibodies, called "inhibitors," against intrinsic factor VIII. Its presentation differs profoundly from congenital hemophilia. Here, we present the case of a 69-year-old patient presenting with right-sided flank pain and hematuria, initially diagnosed with acute pyelonephritis, who was found to have bilateral renal hemorrhage during the course of his hospitalization. Later, after a thorough diagnostic evaluation, he was deemed to have AHA.
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