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Updated: Jun 11, 2025

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
KBr-Mediated Electrochemical Dihydroxylation of Alkenes Using H2O as the Hydroxyl Source
Tao Pan1, Zhichao Shao1, Meng Xue1
1College of Chemistry and Chemical Engineering, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Abstract:
Dihydroxylation of alkenes provides direct access to vicinal diols. Herein, a new electrochemical strategy for dihydroxylation of alkenes in only the presence of KBr is disclosed. Water serves as a green and sustainable hydroxyl source. Cheap KBr acts as both an electrolyte and a catalyst. Both styrenes and unactivated alkenes proceed in the dihydroxylation reactions smoothly to furnish vicinal diols in good yields. The successful synthesis of Cyclandelate, DTD derivative precursors, and a key intermediate for the synthesis of herbicide Metamitron highlights its synthetic utility.
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