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Updated: Jul 12, 2026
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PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke
Published on: June 14, 2018
Increased TSPO, COX-1, and COX-2 Uptake in Bone Marrow Within a Falx Cerebri Ossification
Xuefeng Yan1, Fabrice G Siméon, Victor W Pike
1From the Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Abstract:
Ossification is uncommon, generally asymptomatic, and often incidentally identified in imaging studies. We report on a 54-year-old man who participated as a healthy volunteer in a clinical trial using PET imaging to investigate neuroinflammation. An incidental ossified lesion in the anterior falx cerebri was revealed by MRI. CT scan showed a small hypodense center in the lesion, probably corresponding to bone marrow. The PET scans using 18 F-SF51, 11 C-PS13, and 11 C-MC1 showed increased uptake within this lesion, which was probably related to bone marrow activity within the ossification.
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