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Updated: Jun 11, 2025
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Primary ileal myeloid sarcoma presenting with bowel obstruction: a case report
Hitoshi Minagi1, Nobuhiko Kanaya2, Yoshitaka Kondo1
1Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-Cho, Kita-Ku, Okayama, 700-8558, Japan.
This case study describes a rare instance of primary myeloid sarcoma (MS) in the small intestine of a patient without acute myeloid leukemia (AML). Surgical intervention enabled diagnosis and subsequent chemotherapy for this unusual extramedullary tumor.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Myeloid sarcoma (MS) is an extramedullary tumor of myeloid blasts, often associated with acute myeloid leukemia (AML).
- Primary MS without bone marrow involvement is exceptionally rare.
- This report details a unique case of primary MS originating in the small bowel.
Purpose of the Study:
- To present a rare case of primary ileal myeloid sarcoma.
- To highlight diagnostic challenges and management strategies for small bowel MS.
- To emphasize the importance of surgical intervention for diagnosis and subsequent treatment.
Main Methods:
- A 33-year-old female presented with symptoms of bowel obstruction.
- Imaging (CT) suggested an ileal tumor, with initial suspicion of endometriosis.
- Laparoscopic partial ileal resection was performed, followed by histopathological and immunohistochemical analysis.
- Bone marrow aspiration was conducted postoperatively to rule out leukemia.
Main Results:
- Histopathology confirmed myeloid sarcoma involving the ileum and mesentery.
- The patient had no evidence of bone marrow involvement, confirming primary ileal MS.
- Postoperative recovery was uneventful, and the patient commenced AML-tailored chemotherapy.
Conclusions:
- Small bowel MS is rare and may be overlooked preoperatively.
- Surgical resection is crucial for diagnosis and allows for timely chemotherapy initiation.
- Ensuring surgical safety is paramount for prompt initiation of adjuvant therapy.
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