Related Experiment Video
Updated: Jun 11, 2025

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants
Published on: October 19, 2017
DMSO-Catalyzed Double P-O Bond or Double P-S Bond Formations of Phosphinic Acids
Hui-Qi Yue1, Da-Wei Shi1, Peiqing Zhang2
1School of Chemistry and Chemical Engineering, Yantai University, Yantai, 264005, P. R. China.
Abstract:
A DMSO-catalyzed double P-O bond or double P-S bond formation of phosphinic acid with an O- or S-containing nucleophile has been developed. Under metal-free and mild conditions, this simple procedure provides a compatible and rapid access to a variety of phosphonates and dithiophosphates. The DFT calculation of stabilization energy (SE) and the mechanism studies demonstrated that the "just right" Lewis base property and the relatively "soft" interaction strength with the phosphenium-dication ensure the unique catalytic activity of DMSO in this transformation.
Related Concept Videos
Phosphodiester Linkages
Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
Phosphodiester Bonds Link Nucleotides Together
DNA and RNA are polynucleotides or long chains of nucleotides that are linked together. A nucleotide is...
Preparation of Diols and Pinacol Rearrangement
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
Hybridization of Atomic Orbitals II
Molecular Geometry and Dipole Moments
α-Bromination of Carboxylic Acids: Hell–Volhard–Zelinski Reaction
Carboxylic Acids to Acid Chlorides

