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Updated: Jun 11, 2025

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
Finding MeVO: Identifying Intracranial Medium-Vessel Occlusions at CT Angiography
Daniel R Wayer1, Zack Nigogosyan1, Victoria Xie1
1From the Mallinckrodt Institute of Radiology (D.R.W., Z.N., V.X., A.Y.M., T.A.K., K.D.V., A.R.C., M.S.G.) and Department of Neurology (D.L.H., M.S.G.), Washington University School of Medicine, 510 S. Kingshighway Blvd, Box 8131-50-5, St. Louis, MO 63110.
Abstract:
The development of methods to detect and treat intracranial large-vessel occlusions (LVOs) has revolutionized the management of acute ischemic stroke. CT angiography (CTA) of the head and neck is effective in depicting LVOs and widely used in the evaluation of patients who have had a stroke. Ongoing efforts are now focused on the potential to detect and treat intracranial medium-vessel occlusions (MeVOs), which by definition are smaller than LVOs and thus more difficult to detect with CTA. The authors review common and variant anatomies of medium-sized cerebral arteries and the appearance of a variety of MeVOs on CT angiograms. Possible pitfalls in MeVO detection include rare anatomic variants, calcified thrombi, and stump occlusions. Current recommendations for performing CTA and ancillary methods that might aid in MeVO detection are discussed. Understanding the relevant anatomy and the variety of appearances of MeVOs aids radiologists in identifying these occlusions, particularly in the setting of urgent stroke. ©RSNA, 2024 See the invited commentary by Ospel and Nguyen in this issue.
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