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Paradigm Shift in Eye Banking: From Tissue Retrieval to Cellular Harvesting and Bioengineering
Rashmi Deshmukh1, Harminder S Dua2,3, Jodhbir S Mehta4
1Shantilal Shanghvi Cornea Institute, LV Prasad Eye Institute, Hyderabad, India.
Cornea
|October 4, 2024
Summary
An integrated cell, tissue, and eye bank is essential for modern ocular transplant therapies. It supports traditional corneal transplants and novel cell-based and gene-modified treatments, ensuring high standards and optimal tissue use.
Area of Science:
- Ophthalmology
- Regenerative Medicine
- Tissue Engineering
Background:
- Ocular transplant therapies are evolving beyond traditional corneal transplants.
- Newer treatments involve cell-based therapies and gene-modified products.
- A specialized banking infrastructure is needed to support these advancements.
Purpose of the Study:
- To highlight the critical role of an integrated cell, tissue, and eye bank.
- To describe the comprehensive services required for advanced ocular transplantation.
- To emphasize adherence to rigorous standards in processing and delivery.
Main Methods:
- Integration of cell, tissue, and eye banking services.
- Processing and delivery of diverse transplant materials (corneal, cellular, gene-modified).
- Implementation of rigorous quality standards and tissue utilization optimization.
Main Results:
- An integrated banking model meets the evolving needs of ocular transplantation.
- Comprehensive services enhance tissue utilization and surgeon support.
- Adherence to standards ensures safety and efficacy of diverse transplant materials.
Conclusions:
- Integrated cell, tissue, and eye banks are vital for advancing ocular transplant therapies.
- These banks facilitate the transition from traditional to novel treatments.
- Optimized tissue management and comprehensive services are key to successful outcomes.

