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The 'AfterBurn' Longitudinal Exploratory (ABLE) study: Cohort profile
Martha Druery1, Arpita Das2, Jacelle Warren2
1The University of Queensland, Australia.
Injury
|October 4, 2024
Summary
This study profiles burn patients to understand their quality of life after major burn injuries. Findings offer insights into patient characteristics and factors influencing recovery for better burn care.
Area of Science:
- Medical Research
- Trauma Surgery
- Rehabilitation Medicine
Background:
- Advanced medical treatments increase survival rates for burn patients.
- Understanding long-term quality of life (QoL) is crucial for comprehensive burn care.
- The ABLE study was initiated to address this knowledge gap in burn survivors.
Purpose of the Study:
- To profile the baseline characteristics of adult patients with major burn injuries.
- To establish a cohort for long-term follow-up on quality-of-life outcomes.
- To identify factors influencing the recovery trajectory of burn survivors.
Main Methods:
- Prospective cohort study of 274 adult patients admitted to a state-wide burns centre.
- Baseline data collected within 28 days of injury, with follow-up at 3, 6, and 12 months.
- Health-Related Quality of Life (HRQoL) assessed using SF-12v1 and BSHS-B questionnaires.
Main Results:
- A cohort of 274 patients with a median age of 41.5 years, predominantly male (72%) and non-Indigenous (76%).
- Median Total Body Surface Area (TBSA) burned was 4.75%, with flame burns being the most common injury type (47.1%).
- 37.9% of participants had a pre-existing psychological diagnosis, highlighting potential comorbidities.
Conclusions:
- The ABLE study provides a comprehensive baseline profile of major burn injury patients in Queensland.
- This cohort data is essential for understanding long-term health-related quality of life post-burn.
- Findings will inform future research and clinical practice to improve outcomes for burn survivors.
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