Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.0K
Pharmacovigilance01:19

Pharmacovigilance

2.0K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
2.0K
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

642
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
642
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

429
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
429

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ten Year Update on the Online and Social Media Presence of Australian and New Zealand Urologists.

ANZ journal of surgery·2026
Same author

Periprostatic Nerve Block During Transperineal Prostate Biopsy Under General Anaesthesia: Protocol for a Multicentre Pilot Randomised Controlled Trial.

Cancers·2026
Same author

Beyond Geometrical Symmetry: Revealing Near-Field Optical Chirality on Achiral Gold Nanoparticles under Linear Polarization Excitation.

ACS nano·2026
Same author

The state of urology education in Australia and New Zealand: a regional survey.

BJU international·2026
Same author

Differential Cytokine Profiles in Prostate Cancer Under Treatment: Implications for Prognosis and Synergistic Therapy Design.

Cancers·2026
Same author

A Phase I Study of Hydroxychloroquine and Suba-Itraconazole in Men with Biochemical Relapse of Prostate Cancer (HITMAN-PC): Dose Escalation Results.

Cancer research communications·2026
Same journal

Focal therapy for localized prostate cancer: not all that glitters is gold.

Prostate cancer and prostatic diseases·2026
Same journal

A nationwide histopathology study reflecting the impact of the introduction of MRI in the diagnostic trajectory of prostate cancer in routine clinical care.

Prostate cancer and prostatic diseases·2026
Same journal

En-bloc vs lobe-by-lobe laser prostatectomy: where do we stand?

Prostate cancer and prostatic diseases·2026
Same journal

Response to de Riese et al. regarding "methodological and clinical considerations of MRI-based prostate cancer risk calculators".

Prostate cancer and prostatic diseases·2026
Same journal

Methodological and clinical considerations of MRI-based prostate cancer risk calculators.

Prostate cancer and prostatic diseases·2026
Same journal

Efficacy and safety of darolutamide plus androgen-deprivation therapy in Black patients with metastatic hormone-sensitive prostate cancer from the phase 3 ARANOTE trial.

Prostate cancer and prostatic diseases·2026
See all related articles

Related Experiment Video

Updated: May 1, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.1K

Surveillance after Focal Therapy - a Comprehensive Review.

Giancarlo Marra1, Alessandro Marquis2,3, Michel Suberville4

  • 1Division of Urology, Department of Surgical Sciences, City of Health and Science, Molinette Hospital and University of Turin, Turin, Italy.

Prostate Cancer and Prostatic Diseases
|October 4, 2024
PubMed
Summary
This summary is machine-generated.

Standardized follow-up for focal therapy in prostate cancer is lacking. This review outlines optimal strategies using PSA, MRI, and biopsy for monitoring oncological and functional outcomes after treatment.

More Related Videos

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K
MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

13.9K

Related Experiment Videos

Last Updated: May 1, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.1K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K
MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

13.9K

Area of Science:

  • Oncology
  • Urology
  • Medical Imaging

Background:

  • No standardized follow-up protocols exist for patients after focal therapy (FT) for prostate cancer (PCa).
  • Current monitoring relies on institutional experience and protocols.
  • This review addresses advantageous follow-up strategies and their rationale post-FT.

Purpose of the Study:

  • To conduct a comprehensive literature review on follow-up strategies after focal therapy for prostate cancer.
  • To evaluate oncological and functional outcomes, and complication monitoring.
  • To provide evidence-based recommendations for post-FT patient management.

Main Methods:

  • Narrative literature review investigating various FT follow-up protocols for PCa.
  • Analysis of oncological outcomes (PSA, MRI, biopsy), functional outcomes, and complications.
  • Evaluation of imaging modalities and biomarker utility.

Main Results:

  • Oncological success defined by absence of significant PCa in the treated zone.
  • Recommended follow-up includes periodic PSA, multiparametric MRI (mpMRI) at 6-12 months, and prostate biopsy at 12 months.
  • Functional outcomes assessed via questionnaires; complications monitored early post-treatment.

Conclusions:

  • Focal therapy follow-up requires integrated clinical, radiological, and histological assessment.
  • Further studies are needed to establish standardized, evidence-based follow-up protocols.
  • Risk-adapted approaches are crucial for personalized patient management.