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Oral verrucous carcinoma
Summary
This study investigated 16 cases of verrucous carcinoma in Southern Norway (1975-1982). Findings revealed a female predominance and common occurrence on the mandibular alveolar ridge, often linked to ill-fitting dentures.
Area of Science:
- Oncology
- Oral Pathology
- Dermatology
Background:
- Verrucous carcinoma is a distinct variant of squamous cell carcinoma.
- While considered rare in Scandinavia, a notable cluster of 16 cases occurred in Southern Norway between 1975 and 1982.
Purpose of the Study:
- To investigate the clinical and histological characteristics of verrucous carcinoma in a Norwegian cohort.
- To identify demographic and etiological factors specific to this patient group.
Main Methods:
- Retrospective analysis of 16 diagnosed cases of verrucous carcinoma.
- Review of clinical presentations and histological findings.
- Correlation of patient demographics and habits with tumor characteristics.
Main Results:
- The most frequent site of occurrence was the mandibular alveolar ridge.
- The average patient age was 71 years.
- A female predominance was observed, and tobacco use was notably infrequent.
Conclusions:
- Verrucous carcinoma in this Norwegian cohort exhibited unique epidemiological features, including female predominance and a predilection for the mandibular alveolar ridge.
- Ill-fitting dentures were a common patient complaint.
- Surgical excision is recommended as the primary treatment modality.