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Updated: Jun 11, 2025

Label-Free Quantitative Proteomics Workflow for Discovery-Driven Host-Pathogen Interactions

Label-Free Quantitative Proteomics Workflow for Discovery-Driven Host-Pathogen Interactions

Published on: October 20, 2020

Dissecting host-microbe interactions with modern functional genomics.

Baylee J Russell¹, Manasvi Verma¹, Nolan K Maier¹

¹Department of Microbiology, Harvard Medical School, Boston, MA, USA.

Current Opinion in Microbiology

|October 5, 2024

Summary

This summary is machine-generated.

Functional genomics advances host-microbe interaction research, offering new insights into human health. Innovations in model systems and genetic tools expand the scope of these studies, particularly in the mammalian gut microbiome.

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Published on: July 18, 2013

Area of Science:

Microbiology
Genomics
Host-Pathogen Interactions

Background:

Host-microbe interactions are crucial for basic biological understanding and human health.
Functional genomics has been instrumental in studying these relationships.
Technological progress enables deeper mechanistic insights at greater scale.

Purpose of the Study:

To review the impact of functional genomics on host-microbe interaction research.
To highlight recent technological advancements and their applications.
To discuss emerging opportunities in complex host-microbe systems.

Main Methods:

Review of functional genomics approaches.
Analysis of recent technological innovations.
Exploration of new model systems and genetic tools.

Main Results:

Functional genomics provides scalable, high-resolution mechanistic insights.
Technological advances enhance the study of host-microbe dynamics.
Innovations facilitate research in diverse environments like the mammalian gut.

Conclusions:

Functional genomics is a powerful tool for dissecting host-microbe interactions.
Continued innovation promises significant future discoveries in this field.
Understanding these relationships is key to advancing human health.