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Updated: Jun 11, 2025

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
Published on: April 8, 2016
IG-Net: An Instrument-guided real-time semantic segmentation framework for prostate dissection during surgery for low
Bo Sun1, Zhen Sun2, Kexuan Li2
1Research Unit of Virtual Body and Virtual Surgery Technologies, Division of Colorectal Surgery, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuai Fu Yuan, DongCheng District, Beijing, 100730, China; State Key Laboratory of Virtual Reality Technology and Systems, Beihang University, No. 37 Xueyuan Road, Haidian District, Beijing, 100191, China.
Background And Objective:
Accurate prostate dissection is crucial in transanal surgery for patients with low rectal cancer. Improper dissection can lead to adverse events such as urethral injury, severely affecting the patient's postoperative recovery. However, unclear boundaries, irregular shape of the prostate, and obstructive factors such as smoke present significant challenges for surgeons.
Methods:
Our innovative contribution lies in the introduction of a novel video semantic segmentation framework, IG-Net, which incorporates prior surgical instrument features for real-time and precise prostate segmentation. Specifically, we designed an instrument-guided module that calculates the surgeon's region of attention based on instrument features, performs local segmentation, and integrates it with global segmentation to enhance performance. Additionally, we proposed a keyframe selection module that calculates the temporal correlations between consecutive frames based on instrument features. This module adaptively selects non-keyframe for feature fusion segmentation, reducing noise and optimizing speed.
Results:
To evaluate the performance of IG-Net, we constructed the most extensive dataset known to date, comprising 106 video clips and 6153 images. The experimental results reveal that this method achieves favorable performance, with 72.70% IoU, 82.02% Dice, and 35 FPS.
Conclusions:
For the task of prostate segmentation based on surgical videos, our proposed IG-Net surpasses all previous methods across multiple metrics. IG-Net balances segmentation accuracy and speed, demonstrating strong robustness against adverse factors.

