Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Subconsciousness and No Awareness01:15

Subconsciousness and No Awareness

230
The concept of subconscious awareness refers to the processing of information below the level of conscious thought, which significantly influences both behaviors and decisions. It is also known as waking subconscious awareness. This complex level of cognition operates without the direct awareness of the individual, facilitating rapid and simultaneous handling of multiple information streams.
An illustrative example of subconscious processing is its role in problem-solving. Often, individuals...
230
Understanding Consciousness01:23

Understanding Consciousness

290
Consciousness can be defined as the state of being aware of and able to think about one's existence, sensations, and surroundings. It encompasses two major components: awareness and arousal. Awareness pertains to the recognition of environmental stimuli and internal states. At the same time, arousal refers to the physiological readiness to engage with these stimuli, which varies significantly between states like sleep and wakefulness.
Sleep, a crucial state, is characterized by reduced...
290

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lumbar puncture opening pressure, brain network hub integrity, and delirium in herpes simplex virus encephalitis: a prospective cohort study.

Frontiers in neurology·2026
Same author

Dietary choline intake and incident dementia in middle-aged and older adults: a prospective cohort study and dose-response meta-analysis.

Nutrition journal·2026
Same author

Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain.

CNS neuroscience & therapeutics·2026
Same author

"Digital eye tracking and plasma biomarkers: Distinguishing functional cognitive impairment from Alzheimer's disease biology".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Neural Response to Familiar Names Predicts Outcome of Comatose ICU Patients: A Prospective Observational Cohort Study.

Nature communications·2026
Same author

Landscape of advanced therapy medicinal products in China and future trends.

Science China. Life sciences·2026

Related Experiment Video

Updated: Jun 11, 2025

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

14.5K

Assessing consciousness in acute coma using name-evoked responses.

Jun Hu1, Chunyou Chen2, Min Wu3

  • 1Department of Neurology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.

Brain Research Bulletin
|October 5, 2024
PubMed
Summary
This summary is machine-generated.

Detecting consciousness in acute coma patients is possible using bedside electroencephalography (EEG) and electromyography (EMG). Personalized auditory stimuli, like one's own name, elicited distinct brain and muscle responses, indicating residual awareness.

Keywords:
Acute brain injuryDisorders of consciousnessElectroencephalographyElectromyographySubjects' own name

More Related Videos

Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

9.0K
Author Spotlight: Enhancing Cerebral Ischemia Research with a Simplified Rat Model
03:37

Author Spotlight: Enhancing Cerebral Ischemia Research with a Simplified Rat Model

Published on: July 5, 2024

481

Related Experiment Videos

Last Updated: Jun 11, 2025

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

14.5K
Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

9.0K
Author Spotlight: Enhancing Cerebral Ischemia Research with a Simplified Rat Model
03:37

Author Spotlight: Enhancing Cerebral Ischemia Research with a Simplified Rat Model

Published on: July 5, 2024

481

Area of Science:

  • Neuroscience
  • Clinical Neurology
  • Medical Technology

Background:

  • Assessing consciousness in unresponsive patients, especially those with acute brain injury, is clinically challenging.
  • Existing research primarily focuses on chronic conditions, leaving a gap in understanding acute coma states.
  • Electroencephalography (EEG) has shown promise in detecting brain responses in unresponsive individuals.

Purpose of the Study:

  • To investigate the potential for detecting residual consciousness in acute coma patients using bedside electroencephalography (EEG) and electromyography (EMG).
  • To evaluate the efficacy of an auditory oddball paradigm, incorporating personalized stimuli, in eliciting detectable brain and muscle responses.
  • To differentiate between passive and active listening conditions to identify reliable indicators of awareness.

Main Methods:

  • Recruited 22 patients with acute brain injury (traumatic brain injury or cardiac arrest) and Glasgow Coma Scale (GCS) scores ≤ 8.
  • Utilized bedside EEG and EMG during an auditory oddball paradigm with personalized (own name) and standard names.
  • Compared event-related potentials (ERPs) and EMG spectra between conditions: passive listening and active listening (hand movement cue).

Main Results:

  • Patients showed enhanced ERP responses to their own names, particularly during active listening.
  • Distinct differences in brain network connectivity and increased EMG responses were observed during active listening to personalized stimuli.
  • These findings suggest a measurable neural and muscular response to personally relevant auditory cues in acute coma.

Conclusions:

  • Bedside EEG and EMG can detect signs of residual consciousness in patients with acute coma.
  • Personalized auditory stimuli, especially within an active listening paradigm, can elicit specific responses indicative of awareness.
  • This approach offers a promising tool for assessing consciousness in behaviorally unresponsive patients.