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Emergency department utilization among children with Long COVID symptoms: a COVID-19 research consortium study
Pranav Bhimani1,2, Adina Scheinfeld3, Mangala Rajan4
1Division of General Internal Medicine, Department of Medicine, Weill Cornell Medicine, 420 E 70th street LH 348, New York, NY, USA.
Insights
Children with Long COVID symptoms are significantly more likely to visit the Emergency Department (ED). Specific symptoms like chest pain and fluid imbalances increase the odds of ED visits for pediatric Long COVID patients.
Area of Science:
- Pediatric Health
- Infectious Diseases
- Public Health
Background:
- Long COVID in children is not well understood.
- Persistent symptoms after acute COVID-19 infection are a concern.
- Emergency Department (ED) utilization is a key indicator of healthcare burden.
Purpose of the Study:
- To investigate the association between Long COVID symptoms in children and Emergency Department (ED) utilization.
- To compare ED visit rates in pediatric COVID-19 survivors with and without Long COVID symptoms.
Main Methods:
- Utilized the HealthJump ambulatory database (March 2020-May 2023).
- Defined Long COVID symptoms as occurring 30-180 days post-COVID-19 diagnosis.
- Employed descriptive statistics and multivariable logistic regression to analyze ED utilization.
Main Results:
- 33.6% of 130,010 pediatric COVID-19 cases reported Long COVID symptoms.
- Children with Long COVID had 152% higher odds of ED visits (OR: 2.52).
- Specific symptoms like chest pain (AOR: 3.55) and fluid imbalances (AOR: 3.29) significantly increased ED visit odds.
Conclusions:
- Pediatric Long COVID is associated with substantially higher Emergency Department (ED) utilization.
- Chest pain, fluid imbalances, and generalized pain are strongly linked to increased ED visits in children with Long COVID.
- Findings emphasize the significant impact of pediatric Long COVID on healthcare resources and the need for better management guidelines.
Background And Objectives:
Long COVID, characterized by persistent symptoms beyond the acute infection phase, remains poorly characterized in children. Our study aim is to determine if children who exhibit any symptoms/conditions associated with Long COVID after acute COVID-19 infection have higher Emergency Department (ED) utilization compared to those who do not exhibit these symptoms.
Methods:
Data from the HealthJump ambulatory database from the COVID-19 Research Database Consortium was utilized to identify pediatric COVID-19 cases from March 2020 to May 2023. Long COVID cases were defined based on symptoms/conditions occurring 30-180 days after initial COVID diagnosis. Descriptive statistics and multivariable logistic regression models were used to model the relationship between Long COVID and child ED utilization.
Results:
Out of 130,010 children diagnosed with COVID-19, 43,645 (33.6%) exhibited at least one Long COVID symptom/condition. Children with Long COVID symptoms/conditions had 152% higher odds (OR: 2.52, CI: 2.32-2.73) of ED visits, while those with specific symptoms including "chest pain" had 255% higher odds (AOR: 3.55, CI: 2.73-4.54) and "fluid and electrolyte disturbances" had 229% higher odds (AOR: 3.29, CI: 2.23-4.73) compared to those without those symptoms/conditions.
Conclusion:
This study reveals that children with Long COVID symptoms had notably higher odds of ED visits, with chest pain, fluid imbalances, and generalized pain being most closely linked to such visits. This study highlights the burden of Long COVID on ED providers and underscores the importance of improved guidance for managing Long COVID symptoms in children.
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