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[Peritoneal amyloidosis in Waldenström's macroglobulinemia. X-ray computed tomographic aspects]
Abstract:
A 74 years old man, know to have Waldenström's macroglobulinemia was hospitalized for intestinal obstruction. Upper gastrointestinal barium study revealed an extrinsic stenosis of duodenum. Ultrasonography and abdominal computed tomography revealed a diffuse mesenteric infiltration with medium level echoes and encasing of mesenteric vessels. Histologic examination of biopsies taken at exploratory laparotomy disclosed amyloidosis of the epiploon and mesentery. The review of amyloidosis in macroglobulinemia shows peritoneal amyloidosis to be a very rare event. Sonographic, computed tomographic and pathologic findings of this unusual case are discussed.
Insights
This case study highlights a rare instance of peritoneal amyloidosis in a patient with Waldenström's macroglobulinemia, presenting as intestinal obstruction. Imaging and pathology confirmed mesenteric infiltration, emphasizing the unusual presentation of this condition.
Area of Science:
- Gastroenterology
- Hematology
- Pathology
Background:
- Waldenström's macroglobulinemia is a rare lymphoproliferative disorder.
- Amyloidosis is the abnormal deposition of proteins in tissues.
- Peritoneal involvement in amyloidosis is exceptionally rare.