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"Surgery First" vs. "Endoscopy First" for Pediatric Choledocholithiasis Presenting at the End of the Week - A CARES
Garrett Reid1, Jessica L Rauh1, Elizabeth Wood1
1Wake Forest School of Medicine, Winston Salem, USA.
Insights
A surgery-first approach for pediatric choledocholithiasis significantly reduces hospital stay and time to treatment compared to endoscopy-first strategies. This approach is effective regardless of patient presentation timing, leading to fewer procedures and improved efficiency.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Hepatobiliary Surgery
Background:
- Choledocholithiasis in children is often treated with an endoscopy-first (EF) strategy involving ERCP and LC.
- ERCP availability can be limited on weekends, potentially delaying care.
- A surgery-first (SF) approach may offer advantages in managing pediatric choledocholithiasis.
Purpose of the Study:
- To compare the efficacy of SF versus EF strategies for pediatric choledocholithiasis.
- To evaluate the impact of presentation timing (work week vs. end of week) on treatment outcomes.
- To determine differences in length of stay (LOS) and time to definitive intervention (TTDI).
Main Methods:
- Multicenter, retrospective cohort study of pediatric patients (2018-2023) with suspected choledocholithiasis.
- Defined work week (WW) as Monday-Thursday admission.
- TTDI calculated as time to LC or postoperative ERCP.
Main Results:
- 354 patients analyzed; 61% treated with SF, 39% with EF.
- SF associated with significantly shorter LOS (60.2h WW, 58.3h EoW) compared to EF (88.5h WW, 93.6h EoW).
- SF significantly decreased TTDI (26.4h WW, 28.9h EoW) versus EF (61.4h WW, 72.8h EoW).
- Majority of SF patients (79%) had one procedure, while all EF patients had at least two.
Conclusions:
- Pediatric choledocholithiasis presenting at the end of the week (EoW) leads to longer LOS and TTDI, especially with an EF approach.
- A surgery-first approach reduces procedures, TTDI, and LOS for pediatric choledocholithiasis.
- SF is a more efficient strategy regardless of presentation timing.
Background:
Choledocholithiasis in children is commonly managed with an "endoscopy-first" (EF) strategy (endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC)). Because ERCP availability is often limited at the end of the week (EoW), we hypothesized that a "surgery-first" (SF) approach (LC with intraoperative cholangiogram (IOC) ± transcystic laparoscopic common bile exploration (LCBDE)) would decrease length of stay (LOS) and time to definitive intervention (TTDI).
Methods:
A multicenter, retrospective cohort study was conducted on pediatric patients from 2018 to 2023 with suspected choledocholithiasis. Work week (WW) presentation was defined as admission between Monday to Thursday. TTDI was defined as time to LC or postoperative ERCP (if required).
Results:
Among seven hospitals, there were 354 pediatric patients; 217 (61%) managed with SF (125 WW, 92 EoW) and 137 (39%) managed with EF (74 WW, 63 EoW). SF groups had a shorter LOS for both WW and EoW presentation (60.2 h and 58.3 h vs 88.5 h and 93.6 h respectively; p < 0.05). TTDI decreased in SF (26.4 h and 28.9 h vs 61.4 h and 72.8 h; p < 0.05). All EF patients underwent at least two anesthetics (preoperative ERCP followed by LC) while the majority (79%) of the SF group had only one procedure (LC + IOC ± LCBDE).
Conclusion:
Children who present with choledocholithiasis at EoW have a longer LOS and TTDI. These findings are amplified when children enter an EF pathway. A surgery-first approach results in fewer procedures, decreased TTDI, and shorter LOS, regardless of the time of presentation.
Level Of Evidence:
Level III.
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