[Cefpirome (HR 810). A new broad spectrum cephalosporin]

HR 810 or cefpirome is a new 2-amino-thiazol cephalosporin whose salient characteristic is a bicyclic nucleus, namely cyclopenteno-pyridinium, in position 3. This nucleus imparts a broad spectrum of activity that includes Enterobacteriaceae, Staphylococcus aureus, Pseudomonas aeruginosa, Neisseria, non-D Streptococcus and Haemophilus. Cefpirome is also active, although to a lesser extent, against Streptococcus faecalis and Acinetobacter.