Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pefloxacin: clinical experience].

A Bertrand, F Janbon, J Jourdan

    Pathologie-Biologie
    |June 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Multimodal EEG-fNIRS classification as a clinical tool for bipolar disorder diagnosis.

    Translational psychiatry·2026
    Same author

    Anomalous Pressure Dependence of the Charge Density Wave and Fermi Surface Reconstruction in BaFe_{2}Al_{9}.

    Physical review letters·2025
    Same author

    Rapid synthesis process and characterization for high purity sodium thioantimoniate nonahydrate.

    Dalton transactions (Cambridge, England : 2003)·2022
    Same author

    Monthly anomaly database of atmospheric and oceanic parameters in the tropical Atlantic ocean.

    Data in brief·2022
    Same author

    Omasal flow of nonstructural carbohydrates and nitrogenous compounds in lactating dairy cows fed diets containing timothy cut in the afternoon or morning.

    Journal of dairy science·2021
    Same author

    A case of extreme hydrocephalus in a 67-year-old man whose professional and social lives were normal.

    Neuro-Chirurgie·2021
    Same journal

    Pathologie-biologie·2020
    Same journal

    Antibacterial and antibiofilm activities of Laurus nobilis L. essential oil against Staphylococcus aureus strains associated with oral infections.

    Pathologie-biologie·2015
    Same journal

    [Not Available].

    Pathologie-biologie·2015
    Same journal

    Oxidative damage and histopathological changes in lung of rat chronically exposed to nicotine alone or associated to ethanol.

    Pathologie-biologie·2015
    Same journal

    Biological diagnosis of diabetes mellitus.

    Pathologie-biologie·2015
    Same journal

    Association of CagPAI integrity with severeness of Helicobacter pylori infection in patients with gastritis.

    Pathologie-biologie·2015
    See all related articles

    Pefloxacin effectively treated various infections in 27 patients, showing particular value in bone and meningeal infections. Most patients recovered with minimal side effects, highlighting pefloxacin

    Area of Science:

    • Pharmacology
    • Infectious Diseases
    • Clinical Microbiology

    Context:

    • Pefloxacin, a fluoroquinolone antibiotic, was investigated for its efficacy against a range of bacterial infections.
    • The study included patients with bone and/or joint, respiratory tract, urinary tract, bacteremia, and meningeal infections.

    Purpose:

    • To evaluate the clinical effectiveness and safety of pefloxacin in treating diverse bacterial infections.
    • To assess the susceptibility of isolated pathogens to pefloxacin.
    • To highlight the potential of pefloxacin in treating specific infection types like bone and meningeal infections.

    Summary:

    • Twenty-seven patients received pefloxacin for various infections, with pathogens including Pseudomonas aeruginosa, Enterobacteriaceae, Acinetobacter, Staphylococci (including MRSA), and Streptococcus faecalis.

    Related Experiment Videos

  • Dosages ranged from 800 mg to 1600 mg daily. 21 patients recovered, with three incomplete results and three treatment failures.
  • Minor side effects included mucosal candidiasis and transient rashes; pefloxacin demonstrated particular efficacy in bone and meningeal infections.

    • Impact:

    • Pefloxacin demonstrated significant clinical utility in treating a spectrum of bacterial infections.
    • The findings support the use of pefloxacin, especially for challenging bone and meningeal infections.
    • Further research may explore optimized dosing and combination therapies involving pefloxacin.